Smart Insulin Patch

开展高通量、单细胞尺度的实验，开发大数据分析方法，以获取免疫细胞、免疫反应及宿主与共生微生物互作的信息和知识。

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Smart Insulin Patch

从临床需求出发，寻找与疾病的早期诊断、分子分型、免疫治疗和预后监控相关的生物标志物，开发创新诊断产品。

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Smart Insulin Patch

从高通量实验和免疫大数据分析入手，辅以免疫细胞编辑等工程化技术，开发疾病的中和抗体和细胞治疗新方法。

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关于Immunomics实验室

我们实验室长期致力于应用系统生物学思路，采用高通量多组学技术揭示与健康和疾病相关的人体免疫微环境。

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代表性文章

A Robust Pipeline for TCR and BCR Repertoire Analy

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Guo D, Chen Y, Wu Y, Cheng J, Lin Y, Lai W, Ma W, Yang H, Han L, Ma L, Jia H, Liu X.

Multi-omics characterization of the skin microbiota reveals the anti-aging roles of Stenotrophomonas maltophilia.
Microbiome. 2026

Huang Y, Zhou Q, Gui M, Guo D, Cheng J, Ma W, Shu P, Liu X.

Dynamic multi-omics mechanisms underpinning retinol tolerance: stage-specific reconstruction of skin barrier function and host-microbiome metabolic interactions.
Front Microbiol. 2025

Ye F, Chen M, Huang Y, Zhang R, Li X, Wang X, Han S, Ma L, Liu X.

LightCTL: lightweight contrastive TCR-pMHC specificity learning with context-aware prompt.
Brief Bioinform. 2025

Zhiming Li#, Jingjing Xia#, … Xiao Liu*, Jiucun Wang*.

Characterization of the human skin resistome and identification of two microbiota cutotypes. 
Microbiome. 2021.

Xiao Liu#, Wei Zhang#, Ming Zhao#, et al.

T cell receptor β repertoires as novel diagnostic markers for systemic lupus erythematosus and rheumatoid arthritis.
Annals of the Rheumatic Diseases. 2019.

Wei Zhang, Zheng Su, Yuanping Du,…, Xiao Liu*.

IMonitor: a robust pipeline for TCR and BCR repertoire analysis.
Genetics. 201(2) · August 2015.